BOLALAR VA O‘SMIRLARDA QANDLI DIABET VA UNING KELIB CHIQISH SABABLARI, DAVOLASH VA OLDINI OLISH USULLARI
Keywords:
Qandli diabet, bolalar diabeti, 1-tip diabet, 2-tip diabet, insulin terapiyasi, profilaktika, ovqatlanish rejimi, jismoniy faollik, genetika, immun tizimi.Abstract
Ushbu maqolada bolalar va o‘smirlarda qandli diabetning rivojlanish sabablari, turlari, davolash usullari va profilaktika choralariga oid ilmiy ma’lumotlar tahlil qilingan. 1-tip diabet autoimmun kasallik bo‘lib, insulin ishlab chiqaruvchi beta hujayralarning yo‘q qilinishi natijasida yuzaga keladi. 2-tip diabet esa noto‘g‘ri ovqatlanish, ortiqcha vazn va kam harakatlilik natijasida rivojlanadi. Tadqiqot davomida diabetning oldini olish bo‘yicha sog‘lom turmush tarzini shakllantirish, jismoniy faollikni oshirish va oziq-ovqat rejimini tartibga solish muhimligi ta’kidlangan. Bundan tashqari, diabet diagnostikasi va davolash strategiyalarining samaradorligi tahlil qilinib, kelajakdagi tadqiqot yo‘nalishlari haqida fikr bildirilgan.
References
1. American Diabetes Association. (2023). Standards of Medical Care in Diabetes – 2023. Diabetes Care, 46(1), S1-S64.
2. Atkinson, M. A., Eisenbarth, G. S., & Michels, A. W. (2014). Type 1 diabetes. The Lancet, 383(9911), 69-82.
3. Skyler, J. S., Bakris, G. L., Bonifacio, E., et al. (2017). Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis. Diabetes, 66(2), 241-255.
4. DeFronzo, R. A., Ferrannini, E., Groop, L., et al. (2015). Type 2 diabetes mellitus. Nature Reviews Disease Primers, 1, 15019.
5. Zimmet, P. Z., Magliano, D. J., Herman, W. H., & Shaw, J. E. (2014). Diabetes: a 21st century challenge. The Lancet Diabetes & Endocrinology, 2(1), 56-64.
6. Nathan, D. M. (2015). Diabetes: Advances in Diagnosis and Treatment. JAMA, 314(10), 1052-1062.
7. Weyer, C., Bogardus, C., Mott, D. M., & Pratley, R. E. (1999). The Natural History of Insulin Secretory Dysfunction and Insulin Resistance in the Pathogenesis of Type 2 Diabetes Mellitus. The Journal of Clinical Investigation, 104(6), 787-794.
8. Alberti, K. G. M. M., & Zimmet, P. (1998). Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications. Diabetic Medicine, 15(7), 539-553.
9. Dabelea, D., Mayer-Davis, E. J., Saydah, S., et al. (2014). Prevalence of Type 1 and Type 2 Diabetes Among Children and Adolescents From 2001 to 2009. JAMA, 311(17), 1778-1786.
10. Harding, J. L., Pavkov, M. E., Magliano, D. J., et al. (2019). Global Trends in Diabetes Complications: A Review of Current Evidence. Diabetologia, 62(1), 3-16.
11. Chan, J. C. N., Lim, L. L., Wareham, N. J., et al. (2020). The Lancet Commission on Diabetes: Using Data to Transform Diabetes Care and Patient Outcomes. The Lancet, 396(10267), 2019-2082.
12. Wild, S., Roglic, G., Green, A., et al. (2004). Global Prevalence of Diabetes: Estimates for the Year 2000 and Projections for 2030. Diabetes Care, 27(5), 1047-1053.
13. International Diabetes Federation. (2021). IDF Diabetes Atlas (10th Edition). IDF Publications.
14. Gojka, R., Unwin, N., & Bennett, P. H. (2003). The Burden of Mortality Attributable to Diabetes: Realistic Estimates for the Year 2000. Diabetes Care, 26(9), 2368-2372.
15. Tuomilehto, J., Lindström, J., Eriksson, J. G., et al. (2001). Prevention of Type 2 Diabetes Mellitus by Changes in Lifestyle Among Subjects With Impaired Glucose Tolerance. New England Journal of Medicine, 344(18), 1343-1350.
16. Powers, A. C., & Niswender, K. D. (2019). Diabetes Mellitus: Pathogenesis and Treatment Strategies. Endocrinology & Metabolism Clinics of North America, 48(4), 599-610.
17. Morimoto, A., Tatsumi, Y., Deura, K., et al. (2013). Impact of BMI and the Family History of Diabetes on the Risk of Incident Diabetes. Diabetes Research and Clinical Practice, 100(1), 49-55.
18. NCD Risk Factor Collaboration. (2016). Worldwide Trends in Diabetes Since 1980: A Pooled Analysis of 751 Population-Based Studies with 4.4 Million Participants. The Lancet, 387(10027), 1513-1530.
19. Pambianco, G., Costacou, T., Ellis, D., et al. (2006). Cardiovascular Disease Risk in Type 1 Diabetes. Diabetes Care, 29(8), 1735-1740.
20. Krentz, A. J., & Bailey, C. J. (2005). Oral Antidiabetic Agents: Current Role in Type 2 Diabetes Management. Drugs, 65(3), 385-411.
